Dedup candidate - User Profile Disks (UPD) for RDS vhdx files

I'm trying to determine if User Profile Disk files are good candidates for dedup. I see that with server 2012 r2, VDI disks are good candidates but other running Hyper-V VMs are not.  With both server 2012 and 2012 R2, VHD(X) libraries are also good candidates.  I don't see UPD mentioned anywhere, though.  Any insight is appreciated.  I'd be deduping on a 2012 R2 server BTW.

Thx,

DML

DLovitt