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Is a 'reboot' needed after register modification in Windows Server 2008 R2 SP1?

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Hi

We are trying to modify following parameters, Is a reboot needed to take the modicifation effect ?

HKLM\SYSTEM\CurrentControlSet\Services\mpio\Parameters\RetryInterval

HKLM\SYSTEM\CurrentControlSet\Services\mpio\Parameters\RetryCount

HKLM\SYSTEM\CurrentControlSet\Services\disk\TimeOutValue

Thanks, Good day.


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